Pharmacokinetics of Nasal Esketamine in Patients with Allergic Rhinitis with and Without Nasal Decongestant Pretreatment and in Healthy Subjects with and Without Nasal Corticosteroid Pretreatment

ConclusionsPatients exhibiting symptoms of rhinitis may receive nasal esketamine spray without dose adjustment. In addition, esketamine may be administered 1 h after using a nasal decongestant or corticosteroid.Trial RegistrationThe study was registered in the Clinical Trials (NCT02154334) and EudraCT (2014 ‐000534‐38) registries.
Source: Clinical Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research