Histone methyltransferase SETDB1 promotes osteogenic differentiation in osteoporosis by activating OTX2-mediated BMP-Smad and Wnt/ β-catenin pathways

In conclusion, upregulation of SETDB1 promotes osteogenic differentiation by inhibiting OTX2 and activating t he BMP-Smad and Wnt/β-catenin pathways in osteoporosis.
Source: Human Cell - Category: Cytology Source Type: research