Intermittent theta-burst stimulation combined with physical therapy as an optimal rehabilitation in Parkinson ’s disease: study protocol for a randomised, double-blind, controlled trial

DiscussionThe aim of this study is to demonstrate that iTBS can promote overall function and quality of life in Parkinson ’s disease patients using physiotherapy and that this efficacy may be associated with altered neuroplasticity in exercise-related brain regions. The iTBS combined with physiotherapy training model will be evaluated during a 6-month follow-up period. With significant improvement in quality of life and motor function, iTBS combined with physiotherapy can be considered as a first-line rehabilitation option for Parkinson’s disease. The potential of iTBS to enhance neuroplasticity in the brain should have a more positive impact in increasing the generality and efficiency of physiotherapy, impro ving the quality of life and overall functional status of patients with Parkinson’s disease.Trial registrationChinese Clinical Trial Registry ChiCTR2200056581. Registered on 8 February 2022.
Source: Trials - Category: Research Source Type: clinical trials