Prosthetic joint infection caused by an atypical gram-negative bacilli: Odoribactersplanchnicus

We present an 82 years-old woman who was diagnosed with hip PJI. A radical debridement, prosthetic withdrawal, and spacer introduction was performed. Despite the directed antibiotic therapy against E. coli which was first isolated, the patient persisted clinically febrile. An anaerobic Gram-negative rod was isolated and finally, Odoribacter splanchnicus was identified and confirmed by 16S rRNA gene sequencing. Then, antibiotic bitherapy with ciprofloxacin and metronidazole was started until 6 weeks after surgery. The patient had no signs of infection recurrence after then. This case report also shows the importance of genomic identification of rare microorganisms causing PJI, and also allows setting a directed antibiotic therapy which is crucial for infection eradication.PMID:37315915 | DOI:10.1016/j.anaerobe.2023.102740

Source: Anaerobe - June 14, 2023 Category: Microbiology Authors: Yuri Lara-Taranchenko Pablo S Corona Dolors Rodr íguez-Pardo Paula Salmer ón-Menéndez Marina Vicente Ciurans Mar ía Cristina García-Martínez Luis Carrera Calderer Source Type: research