Genetic analysis and outcomes of Omani children with steroid ‐resistant nephrotic syndrome

ConclusionNPHS2 andNPHS1 genetic variants were the most common inherited causes of SRNS in Omani children. However, patients with variants in several other SRNS causative genes were also identified. We recommend screening for all genes responsible for SRNS in all children who present with this phenotype, which will assist in clinical management decisions and genetic counseling for the affected families.

Source: Molecular Genetics & Genomic Medicine - May 20, 2023 Category: Genetics & Stem Cells Authors: Mohamed S. Al  Riyami, Intisar Al Alawi, Badria Al Gaithi, Anisa Al Maskari, Naifain Al Kalbani, Nadia Al Hashmi, Aisha Al Balushi, Maryam Al Shahi, Suliman Al Saidi, Muna Al Bimani, Fahad Al Hatali, Holly Mabillard, John A. Sayer Tags: ORIGINAL ARTICLE Source Type: research