Diffusion-Weighted Magnetic Resonance Imaging Demonstrates White Matter Alterations in Watershed Regions in Children With Moyamoya Without Stroke or Silent Infarct

Moyamoya is a disease with progressive cerebral arterial stenosis leading to stroke and silent infarct. Diffusion-weighted magnetic resonance imaging (dMRI) studies show that adults with moyamoya have significantly lower fractional anisotropy (FA) and higher mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD) compared with controls, which raises concern for unrecognized white matter injury. Children with moyamoya have significantly lower FA and higher MD in their white matter compared with controls.

Source: Pediatric Neurology - March 15, 2023 Category: Neurology Authors: Banu Ahtam, Marina Solti, Justin M. Doo, Henry A. Feldman, Rutvi Vyas, Fan Zhang, Lauren J. O'Donnell, Yogesh Rathi, Edward R. Smith, Darren Orbach, Alfred P. See, P. Ellen Grant, Laura L. Lehman Tags: Research Paper Source Type: research