Assessment of the uniform field electroretinogram for mouse retinal ganglion cell functional analysis

ConclusionsPERG responses are markedly impaired upon ONC, while UF-ERG responses are not significantly affected by surgical trauma to RGC axons in mice. The more closely related pattern and uniform field ERGs recorded in primates suggests species-specific differences in RGC features or subpopulations corresponding to PERG and UF-ERG response generators, limiting the utility of the UF-ERG for mouse RGC functional analysis.
Source: Documenta Ophthalmologica - Category: Opthalmology Source Type: research