DDX39B facilitates the malignant progression of hepatocellular carcinoma via activation of SREBP1-mediated de novo lipid synthesis

ConclusionsOur study reveals a novel mechanism by which DDX39B facilitates the malignant progression of HCC via activation of SREBP1-mediatedde novo lipogenesis, implicating DDX39B as both a potential predictor of recurrence and prognosis and a promising therapeutic target.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research