Infarct Evolution in Patients with Anterior Circulation Large-Vessel Occlusion Randomized to IV Alteplase and Endovascular Treatment versus Endovascular Treatment Alone [INTERVENTIONAL]

CONCLUSIONS: No statistically significant difference in infarct evolution was found in directly admitted patients who received IV alteplase and endovascular treatment within 4.5 hours of symptom onset versus patients who underwent endovascular treatment alone. Collateral status and occlusion location may be useful predictors of infarct evolution prognosis in patients eligible for IV alteplase who underwent endovascular treatment.

http://www.ajnr.org/cgi/content/abstract/44/4/434?rss=1

Source: American Journal of Neuroradiology - April 10, 2023 Category: Radiology Authors: Hoving, J. W., van Voorst, H., Kappelhof, M., Tolhuisen, M., Treurniet, K. M., LeCouffe, N. E., Rinkel, L. A., Koopman, M. S., Cavalcante, F., Konduri, P. R., van den Wijngaard, I. R., Ghariq, E., Anton Meijer, F. J., Coutinho, J. M., Marquering, H. A., R Tags: INTERVENTIONAL Source Type: research