Perinatal exposure to the fungicide ketoconazole alters hypothalamic control of puberty in female rats

ConclusionnRH secretion and the hypothalamic transcriptome are highly sensitive to perinatal exposure to both DES and KTZ. The identified pathways should be exploredfurther to identify biomarkers for future testing strategies for EDC identification and when enhancing the current standard information requirements in regulation.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research