Non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is a global health problem. It has an estimated prevalence of 25% among adults worldwide; predicted to increase significantly over the coming decade. It is closely related to metabolic syndrome – associated with obesity and type 2 diabetes mellitus (T2DM). NAFLD is defined histologically, ranging from simple steatosis to steatohepatitis, fibrosis and cirrhosis. Triglyceride droplet accumulation in hepatocytes is the first feature in the natural history, leading in some patients to oxidat ive stress, inflammation and the development of fibrosis.
Source: Medicine - Category: Internal Medicine Authors: Anthony George, Jeremy Cobbold Tags: Common European liver disorders Source Type: research
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