Bone marrow-mesenchymal stem cells alleviate microglial Pyroptosis after intracerebral hemorrhage in rat by secreting C1q/tumor necrosis factor-related protein 3
CONCLUSION: BMSCs can inhibit neuroinflammation by inhibiting microglial pyroptosis, thus alleviate ICH symptoms, likely by suppressing the Syk signaling pathway while promoting the PI3K/AKT signaling pathway activation through producing CTRP3.PMID:36958593 | DOI:10.1016/j.expneurol.2023.114387
Source: Experimental Neurology - Category: Neurology Authors: Qinghua Wang Jifeng Piao Yulong Li Huiru Tu Dingyi Lv Libin Hu Run Zhang Zhenzhong Zhong Source Type: research