DAB2IP-knocking down resulted in radio-resistance of breast cancer cells is associated with increased hypoxia and vasculogenic mimicry formation

Conclusions: Our data support that loss of DAB2IP confers radio-resistance of BCa could be due to increased hypoxia, inhibited vascular maturation and promoted VM formation. STAT3 inhibition could be a potential way to overcome such DAB2IP-deficient induced tolerance in BCT.PMID:36947637 | DOI:10.1080/09553002.2023.2194390
Source: International Journal of Radiation Biology - Category: Radiology Authors: Source Type: research