Non-canonical NLRC4 inflammasomes in astrocytes contribute to glioma malignancy

ConclusionThe findings of this study suggest that non-canonical NLRC4 inflammasomes contribute to poor prognosis in patients with glioma and induce an inflammatory microenvironment. We propose the pathological phenomenon of non-canonical NLRC4 inflammasomes and several therapeutic strategies based on the modulation of the inflammatory tumor microenvironment.
Source: Inflammation Research - Category: Research Source Type: research