T7 peptide-decorated exosome-based nanocarrier system for delivery of Galectin-9 siRNA to stimulate macrophage repolarization in glioblastoma

ConclusionOverall, T7-Exo/siGalectin-9 promotes macrophage repolarization and restricts the immunosuppression of GBM, thus providing novel insights into and drug delivery system of immunotherapy for GBM.Graphical abstract

Source: Journal of Neuro-Oncology - March 1, 2023 Category: Cancer & Oncology Source Type: research