Parental divorce, discord, and polygenic risk on children's alcohol initiation and lifetime risk for disorder

CONCLUSIONS: Children's genetic risk for alcohol problems modifies the impact of parental divorce/discord, consistent with an additive model of diathesis-stress interaction, with some differences across ancestry.PMID:36807915 | DOI:10.1111/acer.15042

Source: Alcoholism, Clinical and Experimental Research - February 22, 2023 Category: Addiction Authors: Sally I-Chun Kuo Nathaniel S Thomas Fazil Aliev Kathleen K Bucholz Danielle M Dick Vivia V McCutcheon Jacquelyn L Meyers Grace Chan Chella Kamarajan John R Kramer Victor Hesselbrock Martin H Plawecki Bernice Porjesz Jay Tischfield Jessica E Salvatore Source Type: research