Pharmacological and toxicological studies of a novel goserelin acetate extended-release microspheres in rats

In conclusion, LY01005 displayed a sustained-release profile of goserelin, and exerted a continuous efficacy in vivo in animal models, which had a comparable potency but with a more sustained effect than that of Zoladex®. The safety profile of LY01005 was largely the same with Zoladex®. These results strongly support the planned LY01005 clinical trials.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research