Adherence to Established Blood Pressure Targets and Associated Complications in Patients Presenting with Acute Intracerebral Hemorrhage

ConclusionsIn individuals with nontraumatic/nonaneurysmal ICH, SBP measurements were observed to be  <  140 mm Hg for >  50% of the initial 48 h following admission. Hypotension and relative SBP reduction >  20% were also independent predictors of renal adverse events. SBP reduction >  20% was also an independent predictor of brain ischemia. These data indicate that intensive SBP reduction following ICH predispose patients to secondary organ injury that may impact long-term outcomes. Our data suggest that a more modest lowering of the SBP within 48 h, as recommended in the mos t recent guidelines, may minimize the risk of further adverse events.
Source: Neurocritical Care - Category: Neurology Source Type: research