Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation

The prenylation of proteins is involved in a variety of biological functions. However, it remains unknown whether it plays an important role in the morphogenesis of the cerebellum. To address this question, we...

Source: Molecular Brain - February 13, 2023 Category: Neuroscience Authors: Qi Cheng, Jing Wu, Yingqian Xia, Qing Cheng, Yinjuan Zhao, Peixiang Zhu, Wangling Zhang, Shihu Zhang, Lei Zhang, Yushan Yuan, Chaojun Li, Guiquan Chen and Bin Xue Tags: Research Source Type: research