The neutrophil elastase inhibitor, sivelestat, attenuates acute lung injury in patients with cardiopulmonary bypass

ConclusionAdministration of sivelestat might improve postoperative outcomes in patients with ALI after emergent cardiovascular surgery. Our results show that sivelestat may be considered to protect pulmonary function against inflammatory injury by CPB.Registrationhttp://www.chictr.org.cn/showproj.aspx?proj=166643, identifier ChiCTR2200059102.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research