Development of in Ovo-Compatible NS1-truncated live attenuated influenza vaccines by modulation of hemagglutinin cleavage and polymerase Acidic  X Frameshifting sites

This study demonstrates that targeted genetic mutations can be applied to further attenuate and enhance the safety of live attenuated influenza vaccines to develop future in ovo vaccines for poultry.PMID:36669965 | DOI:10.1016/j.vaccine.2023.01.018

Source: Vaccine - January 20, 2023 Category: Allergy & Immunology Authors: Amir Ghorbani John M Ngunjiri Michael Edward C Abundo Mary Pantin-Jackwood Scott P Kenney Chang-Won Lee Source Type: research