Restoring Study PRGF: a randomized clinical trial on plasma rich in growth factors for knee osteoarthritis
ConclusionsThis reanalysis of Study PRGF found no clinically or statistically significant benefit from PRGF compared to hyaluronic acid. The restoration of Study PRGF shows the urgency of important changes to trial reporting and oversight practices. In the future, timely access to all clinical trial documents is needed to minimize the risk of reporting bias. Similarly, ethics committees should be ready to intervene whenever a case of potential misconduct arises.Trial registrationThis is a RIAT project, whose original trial was approved and registered on 19 December 2007 by the Ethics Committee of the Basque Country, Spain, as BTI-01-EC/07/ART.
Source: Trials - Category: Research Source Type: clinical trials
More News: Clinical Trials | Medical Ethics | Osteoarthritis | Pain | Research | Spain Health | Statistics | Study