Bone marrow mesenchymal stem cell-derived exosomal lncRNA KLF3-AS1 stabilizes Sirt1 protein to improve cerebral ischemia/reperfusion injury via miR-206/USP22 axis

CONCLUSION: BMSC-Exos KLF3-AS1 promoted the Sirt1 deubiquitinating to ameliorate cerebral I/R-induced inflammatory injury via KLF3-AS1/miR-206/USP22 network.PMID:36627572 | DOI:10.1186/s10020-022-00595-1

Source: Molecular Medicine - January 10, 2023 Category: Molecular Biology Authors: Xiaowei Xie Yu Cao Liangping Dai Dingzhou Zhou Source Type: research