Cigarette smoke condensate induces centrosome clustering in normal lung epithelial cells

ConclusionsHere we report a novel role of cyclin D2 in the regulation of centrosome clustering, which could allow the identification of tumors sensitive to cyclin D2 inhibitors. Our data reveal a pathway that can be targeted to inhibit centrosome clustering by interfering with the expression of cyclin D2-associated genes.

Source: Cancer Medicine - January 9, 2023 Category: Cancer & Oncology Authors: Jose Thaiparambil, Chandra S. Amara, Subrata Sen, Nagireddy Putluri, Randa El ‐Zein Tags: RESEARCH ARTICLE Source Type: research