Adolescent raloxifene treatment in females prevents cognitive deficits in a neurodevelopmental rodent model of schizophrenia

We report here that whereas adult female MIA offspring exhibited cognitive deficits in the form of retarded spatial learning, the administration of raloxifene during adolescence was sufficient in preventing these deficits and resulted in intact performance in the MIA group.PMID:36574844 | DOI:10.1016/j.bbr.2022.114276

Source: Behavioural Brain Research - December 27, 2022 Category: Neurology Authors: Viktoria Felgel-Farnholz Elizabeth Barroeta Hlusicka Henriette Edemann-Callesen Alexander Garthe Christine Winter Ravit Hadar Source Type: research