Long-term PT-INR levels and the clinical events in the patients with non-valvular atrial fibrillation: A special reference to low-intensity warfarin therapy.

CONCLUSIONS: The event rates were similar between the low- (1.6-1.99) and high- (2.0-2.59) intensity warfarin therapy groups in aged patients: <70 years and ≥70 years. Time in therapeutic range and a transient fall or rise in PT-INR were risks for clinical events. Blunt head trauma and concomitant use of antiplatelets were risks for intracranial hemorrhage.
PMID: 24440439 [PubMed - as supplied by publisher]

Source: Journal of Cardiology - January 16, 2014 Category: Cardiology Authors: Takarada K, Sato M, Goto M, Saito A, Ikeda Y, Fujita S, Fuse K, Takahashi M, Oguro T, Matsushita H, Kitazawa H, Okabe M, Abe H, Toba K, Yamashina A, Aizawa Y Tags: J Cardiol Source Type: research