Normal and excessive muscle sympathetic nerve activity in heart failure: implications for future trials of therapeutic autonomic modulation

ConclusionBurst frequency and incidence exceeded normative values in only ~53% and ~33% of patients. Such diversity encourages selective deployment of sympatho-modulatory therapies. Clinical characteristics can highlight individuals who may benefit from future personalized interventions targeting pathological sympathetic activation.

Source: European Journal of Heart Failure - December 3, 2022 Category: Cardiology Authors: Mark B. Badrov, Daniel A. Keir, George Tomlinson, Catherine F. Notarius, Philip J. Millar, Derek S. Kimmerly, J. Kevin Shoemaker, Evan Keys, John S. Floras Tags: Research Article Source Type: research