Peak exercise oxygen uptake and changes in renal function in patients after acute myocardial infarction

Ischemic heart events, such as acute myocardial infarction (AMI), cause a decline in renal function,1 –3 and hasten the onset of dialysis in patients with chronic kidney disease (CKD).1 Furthermore, several clinical trials4–7 have demonstrated that concomitant renal dysfunction is an important prognostic factor in patients with AMI. The CREDO-Kyoto AMI, a large registry of patients with AMI in J apan, reported that most of the short-term causes of death ≤ 6 months after percutaneous coronary intervention (PCI) in AMI patients were cardiovascular-related, but two-thirds of the long-term causes of death> 6 months after PCI were non-cardiovascular, and that concomitant renal dysfunction was a powerful factor in defining both short-term and long-term outcomes.
Source: Heart and Lung - Category: Intensive Care Authors: Source Type: research