Disseminated cytomegalovirus infection in a child with langerhans cell histiocytosis

We present a 3-year-old male child with multisystem refractory Langerhans cell histiocytosis, who had very high CMV viremia and disseminated CMV infection with secondary hemophagocytic lymphohistiocytosis and was successfully treated without organ damage and sequelae. Although routine screening is not recommended, CMV viremia/disease needs to be considered in non-transplant immunocompromised children with multisystem involvement with unexplained cytopenia.

Source: Journal of Global Infectious Diseases - November 30, 2022 Category: Infectious Diseases Authors: Polina Siri Iswarya Dhaarani Jayaraman X Joshua Rajan Krithika Prabaharan Source Type: research