Important risk factors for aortic dissection

Important risk factors for aortic dissection Most common risk factor for aortic dissection in the International Registry of Acute Aortic Dissection (IRAD) was hypertension. Hypertension was noted in 76.6% in the IRAD, while Marfan syndrome was noted only in 4.4% and diabetes mellitus in 7.8%. Twenty year data from IRAD has been published. It is a study involving over 7300 cases from over 51 sites in 12 countries. Two thirds were type A dissection and one third type B. Two thirds were men and the mean age was 63 years. In general type A cases underwent surgery and type B cases underwent endovascular repair. There has been a decrease in overall in hospital mortality in type A cases, but not in type B acute aortic dissection [1]. Young patients below the age of 40 years are less likely to have hypertension (34%). They are more likely to have Marfan syndrome (50%) or bicuspid aortic valve (9%). In those above 40 years, Marfan syndrome was only 2% and bicuspid aortic valve was 1%, while hypertension was seen in 72% [2]. References Evangelista A, Isselbacher EM, Bossone E, Gleason TG, Eusanio MD, Sechtem U, Ehrlich MP, Trimarchi S, Braverman AC, Myrmel T, Harris KM, Hutchinson S, O’Gara P, Suzuki T, Nienaber CA, Eagle KA; IRAD Investigators. Insights From the International Registry of Acute Aortic Dissection: A 20-Year Experience of Collaborative Clinical Research. Circulation. 2018 Apr 24;137(17):1846-1860. Januzzi JL, Isselbacher EM, Fattori R, Cooper JV, Smith DE, F...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: General Cardiology Source Type: blogs