Exosomal STAT1 derived from high phosphorus ‑stimulated vascular endothelial cells induces vascular smooth muscle cell calcification via the Wnt/β‑catenin signaling pathway

In conclusion, the present results indicated that exosomal STAT1 derived from HP‑treated HUVECs could promote VSMC calcification, and activation of the Wnt/β‑catenin pathway may be a potential mechanism of the VSMC calcification promoted by exosomes.PMID:36281932 | DOI:10.3892/ijmm.2022.5195

Source: International Journal of Molecular Medicine - October 25, 2022 Category: Molecular Biology Authors: Zheng Qin Yupei Li Jiameng Li Luojia Jiang Zhuyun Zhang Kaixi Chang Qinbo Yang Shanshan Chen Ruoxi Liao Baihai Su Source Type: research