A Meta-analysis of Total Neoadjuvant Therapies Combining Chemoradiotherapy with Induction or Consolidated Chemotherapy for Locally Advanced Rectal Cancer

ConclusionIn this meta-analysis of TNT regimens for rectal cancer, consolidative CT following nCRT was associated with similar PCR, 3-year DFS, LR, R0 resection, compliance, and grade 3 –4 toxicities compared to induction CT prior to nCRT but a higher rate of organ preservation.
Source: Journal of Gastrointestinal Cancer - Category: Cancer & Oncology Source Type: research