Fetal Repair of Neural Tube Defects

Myelomeningocele is the most common congenital neurologic defect, and the only nonlethal disease addressed by fetal surgery. A randomized control trial has established amelioration of the Arnold –Chiari II malformation, reduced ventriculoperitoneal shunt rate, and improvement in distal neurologic function in patients that receive in utero repair. Long-term follow-up of these school-age children demonstrates the persistence of these effects. The use of stem cells in fetal repair is being i nvestigated to further improve distal motor function.
Source: Clinics in Perinatology - Category: Perinatology & Neonatology Authors: Source Type: research