The Case | Hematuria, proteinuria, and renal insufficiency in metastatic prostate cancer

A 75-year-old man with metastatic hormone-resistant prostate cancer and well-controlled hypertension on amlodipine presented with lower limb swelling for 2 weeks. Two years before presentation, he had surgical resection of a destructive bony metastasis in the right innominate bone, followed by stereotactic whole-body radiation therapy and anti-androgen and gonadotropin-releasing hormone antagonists. Despite an 8-month course of prostate-specific membrane antigen (PSMA) –targeted radioligand therapy with 177Lu-PSMA (total 1154 mCi over 6 doses) that was completed 2 months before presentation, the cancer remained progressive.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Make Your Diagnosis Source Type: research