The serotonin receptor 3E variant is a risk factor for female IBS-D

In conclusion, meta-analysis confirmed rs56109847 = rs62625044 as a risk factor for female IBS-D. Expression analysis revealed reducedHTR3E levels in the sigmoid colon of IBS-D patients, which underlines the relevance ofHTR3E in the pathogenesis of IBS-D.
Source: Journal of Molecular Medicine - Category: Molecular Biology Source Type: research