Making a Painless Drain: Proof of Concept
The objective of this study was to develop a novel, cost-effective, easy-to-use, lidocaine-eluting coating to reduce pain associated with postoperative chest tubes. A lidocaine-eluting hydrogel was developed by dispersing lidocaine-loaded nanoparticles in an aqueous solution containing gelatin (5%). Glutaraldehyde (1%) was added to crosslink the gelatin into a hydrogel. The hydrogel was dehydrated, resulting in a thin, stable polymer.
Source: Seminars in Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Anna K. Gergen, Helen J. Madsen, Adam J. Rocker, Allana M. White, Kendra Jones, Daniel T. Merrick, Daewon Park, Jessica Y. Rove Tags: THORACIC – Original Submission Source Type: research
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