In vivo assessment of Lewy body and beta-amyloid copathologies in idiopathic normal pressure hydrocephalus: prevalence and associations with clinical features and surgery outcome

ConclusionsPrevalent LB- and AD-related neurodegenerative pathologies affect a significant proportion of iNPH patients and contribute to cognitive decline (both) and motor impairment (only LB pathology) but do not significantly influence the surgical outcome at 6  months. Their effect on the clinical benefit after surgery over a more extended period remains to be determined.
Source: Fluids and Barriers of the CNS - Category: Neuroscience Source Type: research