'People can't learn about treatments they need': why open access to medical research matters
Campaigners have argued for open access to scientific research since the dawn of the internet – so why is it taking so long?In December 2002, a Belfast teenager made world headlines after his father, Don Simms, won him the legal right to access an experimental drug. Jonathan Simms had been diagnosed with variant Creutzfeldt-Jakob disease (vCJD), a cruel and fatal neurodegenerative condition that gives sufferers an average of one year to live.After receiving the drug pentosan polysulfate, Jonathan lived for another 10 years, defying all medical expectations. The court ruling made medical history: until that point the ...
Source: Guardian Unlimited Science - January 22, 2020 Category: Science Authors: Rachael Pells Tags: Universities Education Higher education Global research Research publishing Science Source Type: news

Coronavirus and Ebola: could open access medical research find a cure?
Campaigners have argued for open access to scientific research since the dawn of the internet – so why is it taking so long?In December 2002, a Belfast teenager made world headlines after his father, Don Simms, won him the legal right to access an experimental drug. Jonathan Simms had been diagnosed with variant Creutzfeldt-Jakob disease (vCJD), a cruel and fatal neurodegenerative condition that gives sufferers an average of one year to live.After receiving the drug pentosan polysulfate, Jonathan lived for another 10 years, defying all medical expectations. The court ruling made medical history: until that point the ...
Source: Guardian Unlimited Science - January 22, 2020 Category: Science Authors: Rachael Pells Tags: Universities Education Higher education Global research Research publishing Science Source Type: news

Creutzfeldt-Jakob disease: a systematic review of global incidence, prevalence, infectivity, and incubation
This review found that although Creutzfeldt-Jakob disease (CJD), particularly iatrogenic CJD, is rare, the incidence of sporadic CJD is increasing. Clinicians and surveillance programmes should maintain awareness of CJD to mitigate future incidences of its transmission. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 9, 2020 Category: Consumer Health News Source Type: news

Role of zinc and copper ions in the pathogenetic mechanisms of traumatic brain injury and Alzheimer's disease - Isaev NK, Stelmashook EV, Genrikhs EE.
The disruption of homeostasis of zinc (Zn2+) and copper (Cu2+) ions in the central nervous system is involved in the pathogenesis of many neurodegenerative diseases, such as amyotrophic lateral sclerosis, Wilson's, Creutzfeldt-Jakob, Parkinson's, and Alzhe... (Source: SafetyLit)
Source: SafetyLit - November 22, 2019 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

How does the prion protein clump? DNA-modulated liquid droplets may explain
(Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem (INBEB)) Researchers at the Federal University of Rio de Janeiro (UFRJ), in Brazil, have found that the prion protein (PrP) suffers liquid-liquid phase separation, and that this mechanism is finely controlled by some DNA sequences. This could explain the formation of irreversible clumping of PrP, structure responsible for neurodegenerative disorders, such as Creutzfeldt-Jakob disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 22, 2019 Category: International Medicine & Public Health Source Type: news

Another Creutzfeldt-Jakob case diagnosed at Moncton Hospital
Diana Paterson is the third person this year to have cataract surgery at the Moncton Hospital, then go on to be diagnosed with Creuztfeld-Jakob disease. An infectious disease doctor says the surgery and the fatal disease aren't connected, and there's no cause for concern. (Source: CBC | Health)
Source: CBC | Health - November 12, 2019 Category: Consumer Health News Tags: News/Canada/New Brunswick Source Type: news

Woman is 3rd person this year diagnosed with Creutzfeldt-Jakob disease at the Moncton Hospital
Diana Paterson is the third person this year to have cataract surgery at the Moncton Hospital, then go on to be diagnosed with Creutzfeldt-Jakob disease. An infectious disease doctor says the surgery and the fatal disease aren't connected, and there's no cause for concern. (Source: CBC | Health)
Source: CBC | Health - November 12, 2019 Category: Consumer Health News Tags: News/Canada/New Brunswick Source Type: news

Treat The Cow, Not The Herd: This Agtech Startup Wants To Prevent Overuse Of Antibiotics
Outside of Mad Cow disease, infectious disease outbreaks in livestock rarely make the news. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - September 19, 2019 Category: Pharmaceuticals Authors: Leah Rosenbaum, Forbes Staff Source Type: news

Plasma transfusions from UK donors could be made available again for people born after 1996
Officials made the ruling in 2004 following the deaths of four people who got 'mad cow disease' from blood transfusions. It meant the NHS had to import blood from Austria and Poland. (Source: the Mail online | Health)
Source: the Mail online | Health - September 11, 2019 Category: Consumer Health News Source Type: news

Blood transfusions from UK donors could be made available again for people born after 1996
Officials made the ruling in 2004 following the deaths of four people who got 'mad cow disease' from blood transfusions. It meant the NHS had to import blood from Austria and Poland. (Source: the Mail online | Health)
Source: the Mail online | Health - September 10, 2019 Category: Consumer Health News Source Type: news

2 Alberta flocks quarantined after fatal disease related to mad cow found in a sheep
Two sheep flocks in central Alberta have been quarantined by the Canadian Food Inspection Agency (CFIA) for scrapie, a fatal disease that affects the central nervous system of both sheep and goats and is related to mad cow disease. (Source: CBC | Health)
Source: CBC | Health - July 18, 2019 Category: Consumer Health News Tags: News/Canada/Calgary Source Type: news

Mad cow disease UK: Could mad cow disease come back? What are the symptoms?
MAD COW DISEASE is a deadly illness which ravaged Britain in the 1980s and 90s. There are now fears it could make a comeback in the UK. What are the symptoms of mad cow disease and will there be another outbreak? (Source: Daily Express - Health)
Source: Daily Express - Health - July 12, 2019 Category: Consumer Health News Source Type: news

What is Mad Cow Disease? And could CJD be about to make a comeback?
MAD COW DISEASE remains seemingly forgotten nearly 20 years after a deadly outbreak of the virus caused a crisis in the UK meat industry. Now scientists fear a resurgence of the disease in the British population. What is Mad Cow disease and could it make a comeback? (Source: Daily Express - Health)
Source: Daily Express - Health - July 11, 2019 Category: Consumer Health News Source Type: news

Mad cow disease: A computational model reveals the mechanism of replication of prions
(Università di Trento) An article published in the journal PLOS Pathogens reports a realistic computational model for the structure and mechanism of replication of prions, infectious agents responsible for mad cow disease and other neurodegenerative disorders of human and animals. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 11, 2019 Category: Infectious Diseases Source Type: news

'I gave my daughter something which killed her'
Annie McVey’s teenage daughter died in 2000 from the human form of mad cow disease, vCJD (variant Creutzfeldt-Jakob disease). (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - July 11, 2019 Category: Consumer Health News Source Type: news

Claire McVey died from the human form of mad cow disease vCJD
Annie McVey’s teenage daughter died in 2000 from the human form of mad cow disease, vCJD (variant Creutzfeldt-Jakob disease). (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - July 11, 2019 Category: Consumer Health News Source Type: news

NIAID scientists develop 'mini-brain' model of human prion disease
(NIH/National Institute of Allergy and Infectious Diseases) Scientists have used human skin cells to create what they believe is the first cerebral organoid system, or 'mini-brain,' for studying sporadic Creutzfeldt-Jakob disease (CJD). CJD is a fatal neurodegenerative brain disease of humans believed to be caused by infectious prion protein. The researchers, from NIH's National Institute of Allergy and Infectious Diseases, hope the human organoid model will enable them to evaluate potential CJD therapeutics and provide greater detail about human prion disease subtypes. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 14, 2019 Category: Infectious Diseases Source Type: news

Brazil lifts suspension of beef exports to China
Brazil's government said on Thursday it has lifted a suspension of beef exports to China after dealing with an atypical case of mad cow disease, sending shares of Marfrig Global Foods, Minerva SA and other Brazilian meatpackers soaring. (Source: Reuters: Health)
Source: Reuters: Health - June 13, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Brazil halts beef exports to China after atypical mad cow case
Brazil has temporarily halted beef exports to China following an atypical case of mad cow disease in leading farm state Mato Grosso, the agriculture ministry said on Monday. (Source: Reuters: Health)
Source: Reuters: Health - June 3, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Brazil's farm ministry confirms temporary suspension of beef exports to China
Brazil's agriculture ministry confirmed on Monday it has temporarily halted Brazilian beef exports to China after a case of atypical mad cow disease. (Source: Reuters: Health)
Source: Reuters: Health - June 3, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

2 'probable' cases of Creutzfeldt-Jakob disease identified at Moncton Hospital
Two separate cases of a rare degenerative brain disorder have been identified at the Moncton Hospital, according to Horizon Health Network. (Source: CBC | Health)
Source: CBC | Health - April 9, 2019 Category: Consumer Health News Tags: News/Canada/New Brunswick Source Type: news

2 cases of Creutzfeldt-Jakob disease at Moncton Hospital not cause for concern, officials say
Two patients who had cataract surgery at Moncton Hospital this winter were later diagnosed with Creutzfeldt-Jakob disease, a rare and fatal brain disease, prompting Horizon Health to notify 700 patients they might have been exposed to the medical instruments used. (Source: CBC | Health)
Source: CBC | Health - April 9, 2019 Category: Consumer Health News Tags: News/Canada/New Brunswick Source Type: news

Health Officials Are Worried That ‘Zombie Deer Disease’ Could Someday Spread to Humans
Officials are worried that a prion disease spreading among deer in the U.S. may someday threaten the health of humans. Chronic wasting disease (CWD), which is nicknamed “zombie deer disease,” gets its name from a range of symptoms. For deer, elk and moose, these include stumbling, listlessness, drooling and rapid weight loss. The fatal disease degrades the brains, spines and bodies of the animals it infects, and there are no known treatments or vaccines. No cases of CWD have been recorded in humans. It has not even been definitely proven that humans can be infected by CWD, though some research has suggested it&...
Source: TIME: Health - February 19, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime public health Source Type: news

Tennessee father-of-four, 33, dies from 'human form of mad cow disease'
Tony Gibson, 33, from Lebanon, Tennessee, was diagnosed with Creutzfeldt-Jakob disease in May 2018. After being given one year to live, he passed away at a nursing home on January 30. (Source: the Mail online | Health)
Source: the Mail online | Health - February 6, 2019 Category: Consumer Health News Source Type: news

Poland detects mad cow disease on farm: OIE
Poland has reported a case of atypical bovine spongiform encephalopathy (BSE) among cattle on a farm near the Czech border, the Paris-based World Organisation for Animal Health (OIE) said on Monday. (Source: Reuters: Health)
Source: Reuters: Health - February 4, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

New skin test detects prion infection before symptoms appear
(Case Western Reserve University) Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein particles often go undetected as they destroy brain tissue, causing memory loss, mobility issues, and ultimately death. Preclinical detection of prions has proven difficult, but new research suggests skin samples hold early signs of prion disease that precede neurologic symptoms. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 22, 2019 Category: Infectious Diseases Source Type: news

Toxic biosolids linked to deadly prion-related illnesses like mad cow disease
(Natural News) Could deadly viruses hiding in the toxic “biosolids” that are being spread all over America’s food crops be at the root of the current epidemic of dementia? According to biosolids expert Craig Monk, there’s strong evidence to suggest so. During a recent behind-the-scenes interview he gave as part of the Brighteon Films Biosludged... (Source: NaturalNews.com)
Source: NaturalNews.com - January 4, 2019 Category: Consumer Health News Source Type: news

Mad Cow Disease Diagnosed in Tennessee Man
A 32-year-old Tennessee man has been diagnosed with the rare human form of mad cow disease, also known as Creutzfeldt-Jakob disease (CJD). (Source: WebMD Health)
Source: WebMD Health - December 24, 2018 Category: Consumer Health News Source Type: news

Man diagnosed with human form of 'mad cow' disease
The human form of 'mad cow' disease affects one in a million people. (Source: ABC News: Health)
Source: ABC News: Health - December 21, 2018 Category: Consumer Health News Tags: Health Source Type: news

Tennessee man diagnosed with human form of 'mad cow' disease: What you should know
The human form of 'mad cow' disease affects one in a million people. (Source: ABC News: Health)
Source: ABC News: Health - December 21, 2018 Category: Consumer Health News Tags: Health Source Type: news

WATCH: What is Mad Cow disease?
Mad Cow disease, or Creutzfeldt-Jakob disease (CJD) in the human form, is a progressive neurological condition. (Source: ABC News: Health)
Source: ABC News: Health - December 20, 2018 Category: Consumer Health News Tags: Health Source Type: news

Tennessee father-of-four given one year to live after diagnosed with rare form of mad cow disease
Tony Gibson, 33, from Lebanon, Tennessee, suddenly became very forgetful last year. Doctors diagnosed him with a rare, degenerative brain disorder known as 'human mad cow disease'. (Source: the Mail online | Health)
Source: the Mail online | Health - December 19, 2018 Category: Consumer Health News Source Type: news

Detecting prions in eyes
Scientists detected abnormal prion proteins in multiple parts of the eye in people who died from Creutzfeldt-Jakob disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 4, 2018 Category: Consumer Health News Source Type: news

Eye Testing May Aid Early Diagnosis of Creutzfeldt-Jakob Disease Eye Testing May Aid Early Diagnosis of Creutzfeldt-Jakob Disease
The presence and levels of prions in the retina, cornea, and other parts of the eye could open a clinical window into early detection of Creutzfeldt-Jakob disease.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - November 29, 2018 Category: Internal Medicine Tags: Neurology & Neurosurgery News Source Type: news

https://img.medscape.com/thumbnail_library/dt_170823_eye_close_up_800x600.jpg https://img.medscape.com/thumbnail_library/dt_170823_eye_close_up_800x600.jpg
The presence and levels of prions in the retina, cornea, and other parts of the eye could open a clinical window into early detection of Creutzfeldt-Jakob disease.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 29, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Eyes of CJD patients show evidence of prions
(NIH/National Institute of Allergy and Infectious Diseases) NIH scientists and colleagues have found evidence of the infectious agent of sporadic Creutzfeldt-Jakob disease (CJD) in the eyes of deceased CJD patients. The finding suggests that the eye may be a source for early CJD diagnosis and raises questions about the safety of routine eye exams and corneal transplants. Sporadic CJD, a fatal neurodegenerative prion disease of humans, is untreatable and difficult to diagnose. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 20, 2018 Category: International Medicine & Public Health Source Type: news

The eyes have it
(University of California - San Diego) By the time symptoms of sporadic Creutzfeldt-Jakob disease (sCJD) are typically discovered, death is looming and inevitable. In a new study, researchers at University of California San Diego School of Medicine with colleagues at the National Institutes of Health and UC San Francisco, report finding tell-tale evidence of the condition's infectious agent in the eyes of deceased sCJD patients, making the eye a potential source for both early CJD detection and prevention of disease transmission. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 20, 2018 Category: International Medicine & Public Health Source Type: news

Creutzfeldt-Jakob disease spreads prions throughout the eyes, researchers find
(American Society for Microbiology) Researchers recently studied the eyes of 11 people with sporadic Creutzfeldt-Jakob disease (sCJD), the most common and well-known prion disorder. This week in mBio, they report finding prion seeds -- the infectious proteins that cause the disease -- spread throughout the eyes of all the patients. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 20, 2018 Category: Infectious Diseases Source Type: news

Scotland's mad cow disease case was a one-off: Tests reveal other cattle do NOT carry the disease 
Out of the five cows analysed on Boghead Farm in Lumsden, near Huntly, Aberdeenshire, only one came back as positive for BSE in what is thought to be a 'sporadic' incident. (Source: the Mail online | Health)
Source: the Mail online | Health - November 8, 2018 Category: Consumer Health News Source Type: news

Kuru disease: What is CANNIBAL infection and how is it spread?
KURU, dubbed a 'zombie disease', shares a link with mad cow disease. What causes Kuru and how does it spread? (Source: Daily Express - Health)
Source: Daily Express - Health - October 19, 2018 Category: Consumer Health News Source Type: news

What is BSE (aka mad cow disease)?
An explanation of the disease - after a case of BSE is confirmed at a farm in Aberdeenshire. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 18, 2018 Category: Consumer Health News Source Type: news

Mad cow disease may have come from 'contaminated food' on Scottish farm
A case of mad cow disease has been confirmed on a farm in Huntly, Aberdeenshire, in what is Scotland's first case of the infection since 2008 and the first in the UK since 2015. (Source: the Mail online | Health)
Source: the Mail online | Health - October 18, 2018 Category: Consumer Health News Source Type: news

Mad cow disease is found on a farm in Scotland as area is placed into lockdown
A case of mad cow disease has been confirmed on a farm in Huntly, Aberdeenshire, in what is Scotland's first case of the infection since 2008 and the first in the UK since 2015. (Source: the Mail online | Health)
Source: the Mail online | Health - October 18, 2018 Category: Consumer Health News Source Type: news

Scottish government identifies case of mad cow disease
Scotland's government said on Thursday that a case of bovine spongiform encephalopathy (BSE), or mad cow disease, had been discovered on a farm in Aberdeenshire. (Source: Reuters: Health)
Source: Reuters: Health - October 18, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

New York hunter, 61, dies after eating SQUIRREL BRAINS
A 61-year-old man from Rochester, New York, was diagnosed with, and later died from, Creutzfeldt-Jakob disease in 2015 after he ate squirrel brains that were contaminated with infectious proteins. (Source: the Mail online | Health)
Source: the Mail online | Health - October 16, 2018 Category: Consumer Health News Source Type: news

Patient with Creutzfeldt-Jakob disease to receive experimental treatment
For the first time, a patient with the rare, fatal brain disease Creutzfeldt-Jakob will be given an antibody compound developed in London. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 9, 2018 Category: Consumer Health News Source Type: news

Mad cow disease found in a Florida animal, USDA reports  
The USDA confirmed Wednesday that one animal intended to be used for beef in Florida had mad cow disease, bu says it has put down the animal and seen no evidence of brain wasting in people. (Source: the Mail online | Health)
Source: the Mail online | Health - August 30, 2018 Category: Consumer Health News Source Type: news

Florida finds atypical mad cow case, no human threat seen
A 6-year-old beef cow in Florida tested positive for bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, the U.S. Department of Agriculture said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - August 29, 2018 Category: Consumer Health News Tags: healthNews Source Type: news