Effects of Fasting and Phoenix dactylifera on the Expression of Major Drug-Metabolizing Enzymes in the Mouse Livers

CONCLUSION: It is concluded from this study that fasting and consuming of Phoenix dactylifera upregulated the mRNA expression of major drug-metabolizing enzymes in mouse livers. These findings may explain, at least partly, the variation of drug response during fasting of the month of Ramadan and would direct future clinical studies in optimizing dosing of pharmacotherapeutic regimen.PMID:35993475 | DOI:10.2174/1389200223666220820105330
Source: Current Drug Metabolism - Category: Drugs & Pharmacology Authors: Source Type: research