A platform trial design for preventive vaccines against Marburg virus and other emerging infectious disease threats

CONCLUSION: This event-driven design takes into the account the potentially sporadic spread of Marburg virus. The proposed trial design may be applicable for other pathogens against which effective vaccines are not yet available.PMID:35866633 | DOI:10.1177/17407745221110880

Source: Clinical Trials - July 22, 2022 Category: Research Authors: Ira M Longini Yang Yang Thomas R Fleming C ésar Muñoz-Fontela Rui Wang Susan S Ellenberg George Qian M Elizabeth Halloran Martha Nason Victor De Gruttola Sabue Mulangu Yunda Huang Christl A Donnelly Ana-Maria Henao Restrepo Source Type: research