Catheter ablation for atrial fibrillation in patients with chronic kidney disease and on dialysis – a meta-analysis and review

Background: Atrial fibrillation (AF) is common in chronic kidney disease (CKD) patients and is difficult to treat with antiarrhythmics and anticoagulants due to abnormal metabolism and increased side effects. Catheter ablation, if successful, may be a safer alternative. This review aims to analyse the effect of CKD or haemodialysis (HD) on recurrence of AF after catheter ablation . This review evaluates efficacy of catheter ablation therapy in CKD and haemodialysis (HD) patients by with single catheter ablation therapy. Methods: MEDLINE, and Embase, and Pubmed databases were searched until December 2020. Two authors abstracted the data independently. Relative risks were derived using random-effects meta-analysis. Results: Of the initially identified 520 782 studies, 65 and 34 observational studies on CKD and HD patients respectively were found reporting AF recurrence rates. During a mean (SD) follow-up of 25.5 (9.8) months, CKD patients have a higher risk of AF recurrence compared to patients without CKD (RR 2.34, 95% CI 1.36-4.02, p
Source: Cardiorenal Medicine - Category: Urology & Nephrology Source Type: research