Ex-vivo activation of a liposomal prodrug of mitomycin C by human tumors

ConclusionsTumor tissue homogenates activate MLP with greater efficiency than the surrounding normal tissues, but far less than liver and adipose tissue. These observations demonstrate the bioavailability of liposomal MLP in human tumors, and its pharmacologic potential in cancer therapy.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research