Early improvement after IV tPA at the largest safety-net hospital in New England: the Boston Medical Center experience (P6.232)

CONCLUSIONS: Neurologic improvement within 24 hours was seen in half of our cohort. Patients who improved benefited despite high baseline NIHSS scores and multiple comorbidities. Interestingly time to needle onset was not a significant predictor for early improvement. Further efforts to include underserved populations in clinical trials should be undertaken to clarify key predictors of early improvement after tPA infusion in this population.Disclosure: Dr. Tawakul has nothing to disclose. Dr. Ge has nothing to disclose. Dr. Lau has nothing to disclose. Dr. Nguyen has nothing to disclose. Dr. Romero has nothing to disclose. Dr. Babikian has nothing to disclose. Dr. Kase has nothing to disclose. Dr. Masoud has nothing to disclose.

Source: Neurology - April 8, 2015 Category: Neurology Authors: Tawakul, A., Ge, G., Lau, H., Nguyen, T., Romero, J., Babikian, V., Kase, C., Masoud, H. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Thrombolysis Source Type: research