Transient ischemic attacks in post-menopausal women with history of migraines have lower risk for subsequent ischemic strokes (P2.306)

BACKGROUND: TIAs and migraines have both been found to increase the risk of ischemic strokes. The risk for ischemic strokes may be further increased in patients with both of these risk factors. OBJECTIVE: To compare the risk of ischemic strokes in women with and without a history of migraine following a TIA. METHODS: The Observational Study (OS) of the Women’s Health Initiative (WHI) was the observational component of the WHI Study. We analyzed the 93,676 women aged 50-79 years, who participated in the OS over a period of 12±1 years. We determined the risk of incident ischemic stroke following TIAs in women with and without history of migraine. A logistic regression analysis was used to determine the differential risk of ischemic stroke in women with and without history of migraine after adjusting for potential confounders. RESULTS: A total of 133 of the 93676 women without history of migraine and 20 women with history of migraine from the same population developed ischemic strokes. Logistic regression analysis demonstrated that women without history of migraine had a higher odds of developing ischemic stroke [OR 1.9 (95[percnt]CI 1.5-2.5) p
Source: Neurology - Category: Neurology Authors: Tags: Cerebrovascular Disease and Interventional Neurology: Education and TIA Source Type: research

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CONCLUSIONS: Perceived devaluation was extremely prevalent among street-involved youth in our sample. We also observed that youth most in need of health and social services were significantly more likely to report high levels of perceived devaluation which may result in a reluctance to seek out key services and supports. These findings highlight the need to implement stigma reduction interventions for vulnerable youth in this setting. PMID: 30526206 [PubMed - as supplied by publisher]
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
Influence of Βeta-Cryptoxanthin Supplementation on Ovarian Reserve and Fertility Status in Aged Wistar Rats. J Diet Suppl. 2018 Dec 08;:1-13 Authors: Pearce K, Tremellen K Abstract Previous observational studies have suggested that β-cryptoxanthin, a micronutrient present in yellow and orange fruit and vegetables, may help delay the onset of menopause. Given the widespread social trend of delaying pregnancy, the possibility that β-cryptoxanthin supplementation may delay age-related loss of fertility and onset of menopause is of significant interest. In a parallel study, either saline or ...
Source: Journal of Dietary Supplements - Category: Nutrition Tags: J Diet Suppl Source Type: research
Authors: Barbanti P, Grazzi L, Egeo G Abstract INTRODUCTION: Migraine is increasingly recognized as an extremely burdensome and disabling disorder in both children and adolescents. A proper treatment plan is needed to improve the quality of life of both children and families as well as to minimize the risk of disease progression. Areas covered: This review focuses on the current pharmacotherapy for acute migraine in pediatric populations, taking into account specific considerations for those drugs tested in randomized, placebo-controlled trials (RCTs). Expert opinion: A large number of RCTs have documented the effi...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Authors: Wang P, Li X, He C, Zhai Y, Sun H, Zhang Y, Wang H, Wang Y, Zhao J, Tang Y Abstract OBJECTIVES: The relationship between hyperuricemia (HUA) and prognosis of acute ischemic stroke (AIS) is unclear. This prospective cohort study aims to evaluate potential value of HUA as a prognostic factor for AIS independent of diabetic status. METHODS: A total of 1041 consecutive patients aged from 25 to 96 with AIS were included. 340 (32.7%) had diabetes and 246 (23.6%) had HUA. Diabetic patients were stratified by gender or age. Multivariate logistic regression was used to analyse the association between HUA and pr...
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
We present the case of a young person, of the male persuasion, without any personal pathological history, found unconscious and presenting signs of violence. The patient is emergency hospitalized presenting coma, convulsive syndrome, severe metabolic acidosis and a positive result for alcoholism. Anamnestic data is extremely poor. The results of the clinical and paraclinical examinations suggest a possible poisoning with toxic alcohols. Despite the drug treatment and the hemodialysis, the evolution is unfavorable, resulting in death one week after admission. Through the forensic examination, the followings were found: cere...
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research
Authors: Mustafa ER, Tudoraşcu DR, Giucă A, Toader DM, Foarfă MC, Puiu I, Istrate-Ofiţeru AM Abstract A 46-year-old female diagnosed several years ago with arterial hypertension and an ischemic stroke with significant recovery was admitted for dyspnea on usual physical activity and fatigue. Physical examination revealed signs of heart failure with crackles on both lung bases, distented jugular veins, accentuated pulmonic valve closure (P2) and tricuspid regurgitation murmur. Echocardiography identified a large tumor in the left atrium, suggestive of atrial myxoma, which caused a severe functional mitral stenosi...
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research
Authors: Sfarti VC, Bălan G, Chiriac AŞ, Stanciu C, Bălan G, Gafencu-Şavlovschi D, Trifan AV Abstract AIM: The aim of our study was to compare baseline characteristics and clinical data as well as endoscopic retrograde cholangiopancreatography (ERCP) results in patients with and without periampullary diverticulum (PAD). PATIENTS, MATERIALS AND METHODS: A single center retrospective analysis was conducted from June 2016 to June 2017 and the patients that had undergone ERCP were divided into two groups, according to the presence (Group A, 43 patients) or absence (Group B, 55 patients) of PAD. RESULTS: Mea...
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research
Authors: Neagu TP, Ţigliş M, Popescu A, Enache V, Popescu ŞA, Lascăr I Abstract Ledderhose disease or plantar fibromatosis is a rare hyperproliferative disorder of the plantar aponeurosis, clinically characterized by nodules situated especially on the medial border of the foot. It is histopathologically associated with Dupuytren's disease. This disease has some risk factors, like old age, alcohol or nicotine abuse, liver dysfunction, trauma or exposure to vibrations and autoimmune disorders, but the exact etiology is still unknown. Even though it is benign, the local manifestations can be aggressive, leading to...
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research
Adding ipsilateral, proximal endovascular (IPE) intervention to carotid endarterectomy (CEA) for the treatment of tandem bifurcation and supra-aortic trunk disease is controversial. Some suggest that this combined strategy (CEA  + IPE) confers no risk over isolated CEA (ICEA). Others disagree, reserving CEA + IPE for symptomatic patients. Using the Vascular Quality Initiative (VQI), this study assessed the effect of adding IPE to CEA on stroke and death risk. We further weighed CEA + IPE outcomes in the context of sympt omatic status and Society for Vascular Surgery guidelines.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Clinical paper Source Type: research
Authors: Lamas C, García-Martínez A, Cámara R, Fajardo-Montanana C, Viguera L, Aranda I Abstract Silent somatotroph pituitary neuroendocrine tumors (or silent growth hormone pituitary neuroendocrine tumors, SGH-PitNET) are neoplasias with positive immunostaining for growth hormone (GH), in patients with no signs and symptoms of acromegaly nor biochemical evidence of GH hypersecretion. From a clinical stand-point they are considered and managed as non-functioning pituitary tumors, since they usually come to evidence due to mass-effects (headache, visual impairment, hypopituitarism) or as asympto...
Source: Minerva Endocrinologica - Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
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