Effects of MCU mediated Ca2+ homeostasis on ovarian cancer cell SKOV3 proliferation, migration and transforming

CONCLUSIONS: Down-regulation of MCU inhibited SKOV3 cell proliferation, migration, and transforming via disturbing Ca2+ homeostasis and decreasing ROS production. MICU1and phosphorylation of Akt was associated with MCU -mediated ovarian cancer malignancy.PMID:35718978 | DOI:10.2174/1566524022666220617143754

Source: Current Molecular Medicine - June 20, 2022 Category: Molecular Biology Authors: Guanqun Wang Lantao Zhao Man Jiang Tian Tian Yingying Mei Guangming Fu Na Zhou Source Type: research