Viruses, Vol. 14, Pages 1258: Molecular Characterisation and Phylogeny of Tula Virus in Kazakhstan

Viruses, Vol. 14, Pages 1258: Molecular Characterisation and Phylogeny of Tula Virus in Kazakhstan Viruses doi: 10.3390/v14061258 Authors: Nur Tukhanova Anna Shin Nurkeldi Turebekov Talgat Nurmakhanov Karlygash Abdiyeva Alexandr Shevtsov Toktasyn Yerubaev Gulnara Tokmurziyeva Almas Berdibekov Vitaliy Sutyagin Nurbek Maikanov Andrei Zakharov Ilmars Lezdinsh Lyazzat Yeraliyeva Guenter Froeschl Michael Hoelscher Stefan Frey Edith Wagner Lukas Peintner Sandra Essbauer Orthohantaviruses are zoonotic pathogens that play a significant role in public health. These viruses can cause haemorrhagic fever with renal syndrome in Eurasia. In the Republic of Kazakhstan, the first human cases were registered in the year 2000 in the West Kazakhstan region. Small mammals can be reservoirs of orthohantaviruses. Previous studies showed orthohantavirus antigens in wild-living small mammals in four districts of West Kazakhstan. Clinical studies suggested that there might be further regions with human orthohantavirus infections in Kazakhstan, but genetic data of orthohantaviruses in natural foci are limited. The aim of this study was to investigate small mammals for the presence of orthohantaviruses by molecular biological methods and to provide a phylogenetic characterization of the circulating strains in Kazakhstan. Small mammals were trapped at 19 sites in West Kazakhstan, four in Almaty region and at seven sites around Almaty city during all seasons ...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research