HIV-1 pretreatment drug resistance negatively impacts outcomes of first-line antiretroviral treatment

Conclusion: PDR was detected in 13% of study participants. PDR significantly increased the risk of virological failure of EFV-based ART. Accumulation of resistance at failure and inability to achieve virological resuppression illustrates the profound impact of PDR on treatment outcomes.
Source: AIDS - Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research