Smartphone Use in the Management of Neurological Emergencies: A Simulation-Based Study
ConclusionsParticipants commonly used smartphones in simulated neuroemergencies but use didn ’t confer improved clinical performance. Less experienced participants were the most likely to use smartphones and less likely to arrive at correct conclusions, and thus are the most likely to benefit from an evidence-based smartphone application for neuroemergencies. (Source: Neurocritical Care)
Source: Neurocritical Care - May 21, 2024 Category: Neurology Source Type: research
Electroconvulsive Therapy in Refractory and Super-Refractory Status Epilepticus in Adults: A Scoping Review
ConclusionsThere are level-4 Oxford Centre for Evidence-Based Medicine evidence and low-level Grading of Recommendations Assessment Development and Education evidence that suggest ECT as a treatment option for RSE and SRSE. In light of the limitations of the existing evidence, clinicians should carefully consider individual patients ’ clinical contexts when deciding on the appropriateness of ECT as a treatment option. Further research, including prospective studies with controlled designs, is needed to elucidate the efficacy, safety, and optimal regime of ECT in the management of RSE and SRSE. (Source: Neurocritical Care)
Source: Neurocritical Care - May 20, 2024 Category: Neurology Source Type: research
Acute-Phase Neurofilament Light and Glial Fibrillary Acidic Proteins in Cerebrospinal Fluid Predict Long-Term Outcome After Severe Traumatic Brain Injury
ConclusionsThis study shows that initial high concentrations of NfL and GFAP in CSF are both associated with higher odds for GOS 1 –3 outcome 1 year and 10–15 years after an sTBI, implicating its potential usage as a prognostic marker in the future. (Source: Neurocritical Care)
Source: Neurocritical Care - May 20, 2024 Category: Neurology Source Type: research
Verification of Death by Neurologic Criteria: A Survey of 12 Organ Procurement Organizations Across the United States
ConclusionsAccurate DNC determination is important to maintain public trust. Nearly all OPO respondents reported a process to verify hospital DNC policies and practices with medical society guidelines. Many reported concerns about clinician knowledge surrounding DNC determination and guideline-discordant policies and practices. Educational and regulatory advocacy efforts are needed to facilitate systematic implementation of guideline-concordant practices across the country. (Source: Neurocritical Care)
Source: Neurocritical Care - May 15, 2024 Category: Neurology Source Type: research
Early Celecoxib Use in Spontaneous Intracerebral Hemorrhage is Associated with Reduced Mortality
ConclusionsThere exists a growing interest in using COX-2 as a potential target strategy for neuroprotection in patients with sICH, with some evidence of a mortality benefit in small cohort studies. This study shows that early celecoxib use is associated with decreased mortality in patients with sICH. (Source: Neurocritical Care)
Source: Neurocritical Care - May 15, 2024 Category: Neurology Source Type: research
Hyperbaric Oxygen Therapy Reduces the Traumatic Brain Injury –Mediated Neuroinflammation Through Enrichment of Prevotella Copri in the Gut of Male Rats
ConclusionsOur study demonstrated how the neuroprotective effects of HBO after acute TBI might act through reshaping the TBI-induced gut dysbiosis and reversing the TBI-mediated decrease ofPrevotella copri. (Source: Neurocritical Care)
Source: Neurocritical Care - May 15, 2024 Category: Neurology Source Type: research
PaCO2 Association with Outcomes of Patients with Traumatic Brain Injury at High Altitude: A Prospective Single-Center Cohort Study
ConclusionsHigher PaCO2 levels are associated with an unfavorable outcome in ventilated patients with TBI. These results underscore the importance of PaCO2 levels in patients with TBI and whether it should be adjusted for populations living at higher altitudes. (Source: Neurocritical Care)
Source: Neurocritical Care - May 13, 2024 Category: Neurology Source Type: research
Pharmacologic Venous Thromboembolism Prophylaxis in Patients with Nontraumatic Subarachnoid Hemorrhage Requiring an External Ventricular Drain
ConclusionsIn this retrospective study of patients with nontraumatic SAH with an EVD who received enoxaparin or UFH VTE prophylaxis or no VTE prophylaxis, there was no statistically significant difference in the incidence of VTE or secondary ICH. For patients receiving prophylactic enoxaparin, achieving higher steady-state target anti-Xa levels may be associated with a lower incidence of VTE without increasing the risk of secondary ICH. (Source: Neurocritical Care)
Source: Neurocritical Care - May 10, 2024 Category: Neurology Source Type: research
The Effects of IRL-1620 in Post-ischemic Brain Injury: A Systematic Review and Meta-analysis of Experimental Studies
ConclusionsAccording to the above, in animal MCAO models, IRL-1620 enhanced neurogenesis and neuroprotection and improved outcome. Future studies are needed to expand our understanding of its effects in human study participants with acute ischemic stroke as well as in other common causes of cerebral ischemia including cardiac arrest. (Source: Neurocritical Care)
Source: Neurocritical Care - May 9, 2024 Category: Neurology Source Type: research
Neuromonitoring in Pediatric Neurocritical Care: An Introduction
(Source: Neurocritical Care)
Source: Neurocritical Care - April 30, 2024 Category: Neurology Source Type: research
Mental Health Services in Postcardiac Arrest Care
(Source: Neurocritical Care)
Source: Neurocritical Care - April 29, 2024 Category: Neurology Source Type: research
Statins in Subarachnoid Hemorrhage to Prevent Delayed Cerebral Ischemia: Old Drugs for New Strategies?
(Source: Neurocritical Care)
Source: Neurocritical Care - April 29, 2024 Category: Neurology Source Type: research
The Early Benchmarks of Outcome Determination in Cerebral Hemorrhage
(Source: Neurocritical Care)
Source: Neurocritical Care - April 29, 2024 Category: Neurology Source Type: research
Ictal –Interictal Continuum in the Pediatric Intensive Care Unit
ConclusionsRhythmic and periodic patterns and subsequently the IIC are commonly seen in the PICU and carry a high association with cerebral injury. Additionally, the IIC, seen in more than 10% of critically ill children, is associated with ES. The independent impact of RPP and IIC patterns on secondary brain injury and need for treatment of these patterns independent of ES requires further study. (Source: Neurocritical Care)
Source: Neurocritical Care - April 26, 2024 Category: Neurology Source Type: research
A Comprehensive Insight into Coma Prevalence in Chilean Critical Care Units
(Source: Neurocritical Care)
Source: Neurocritical Care - April 26, 2024 Category: Neurology Source Type: research
