Accuracy of brain natriuretic peptide and N-terminal brain natriuretic peptide for detecting paediatric pulmonary hypertension: a systematic review and meta-analysis
CONCLUSIONS: Both BNP and NT-proBNP are good markers for differentiating paediatric PH patients from non-PH individuals.PMID:38753384 | DOI:10.1080/07853890.2024.2352603 (Source: Annals of Medicine)
Source: Annals of Medicine - May 16, 2024 Category: Internal Medicine Authors: Ruixi Zhou Yupeng Lei Long Ge Qian Mao Liuping Yang Xia Qiu Source Type: research
Molecular methods in cancer diagnostics: a short review
CONCLUSION: After conducting an in-depth study on the molecular methods in cancer genetics, it is evident that these cutting-edge technologies have revolutionized the field of oncology, providing researchers and clinicians with powerful tools to unravel the complexities of cancer at the genetic level. The integration of molecular methods techniques has not only enhanced our understanding of cancer etiology, progression, and treatment response but has also opened new avenues for personalized medicine and targeted therapies, leading to improved patient outcomes.PMID:38753424 | DOI:10.1080/07853890.2024.2353893 (Source: Annals of Medicine)
Source: Annals of Medicine - May 16, 2024 Category: Internal Medicine Authors: Tanushree Budhbaware Jaishriram Rathored Sandesh Shende Source Type: research
Management of hypertension addressing hyperuricaemia: introduction of nano-based approaches
Ann Med. 2024 Dec;56(1):2352022. doi: 10.1080/07853890.2024.2352022. Epub 2024 May 16.ABSTRACTUric acid (UA) levels in blood serum have been associated with hypertension, indicating a potential causal relationship between high serum UA levels and the progression of hypertension. Therefore, the reduction of serum UA level is considered a potential strategy for lowering and mitigating blood pressure. If an individual is at risk of developing or already manifesting elevated blood pressure, this intervention could be an integral part of a comprehensive treatment plan. By addressing hyperuricaemia, practitioners may subsidize t...
Source: Annals of Medicine - May 16, 2024 Category: Internal Medicine Authors: Koyeli Girigoswami Radhakrishnan Arunkumar Agnishwar Girigoswami Source Type: research
Effect of on-demand vs continuous prescription of proton pump inhibitors on symptom burden and quality of life: results of a real-world randomized controlled trial in primary care patients with gastroesophageal reflux disease
CONCLUSION: In real-world settings, both continuous and on-demand PPI prescriptions resulted in similar increases in PPI consumption with no difference in treatment effects. Achieving an adequate PPI dose to alleviate reflux symptom burden improves quality of life in GERD patients. EudraCT number 2014-001314-25.PMID:38753973 | DOI:10.1080/07853890.2024.2354683 (Source: Annals of Medicine)
Source: Annals of Medicine - May 16, 2024 Category: Internal Medicine Authors: Anna Andreasson Lars Agr éus Nikolaos Mastellos Grzegorz Bli źniuk Dorota Wa śko-Czopnik Agapi Angelaki Eirini Theodosaki Christos Lionis Karin Hek Robert Verheij Ellen Wright Stevo Durbaba Jean Muris Piotr Br ódka Stanislaw Saganowski Jean-Francois E Source Type: research
Accuracy of brain natriuretic peptide and N-terminal brain natriuretic peptide for detecting paediatric pulmonary hypertension: a systematic review and meta-analysis
CONCLUSIONS: Both BNP and NT-proBNP are good markers for differentiating paediatric PH patients from non-PH individuals.PMID:38753384 | DOI:10.1080/07853890.2024.2352603 (Source: Annals of Medicine)
Source: Annals of Medicine - May 16, 2024 Category: Internal Medicine Authors: Ruixi Zhou Yupeng Lei Long Ge Qian Mao Liuping Yang Xia Qiu Source Type: research
Molecular methods in cancer diagnostics: a short review
CONCLUSION: After conducting an in-depth study on the molecular methods in cancer genetics, it is evident that these cutting-edge technologies have revolutionized the field of oncology, providing researchers and clinicians with powerful tools to unravel the complexities of cancer at the genetic level. The integration of molecular methods techniques has not only enhanced our understanding of cancer etiology, progression, and treatment response but has also opened new avenues for personalized medicine and targeted therapies, leading to improved patient outcomes.PMID:38753424 | DOI:10.1080/07853890.2024.2353893 (Source: Annals of Medicine)
Source: Annals of Medicine - May 16, 2024 Category: Internal Medicine Authors: Tanushree Budhbaware Jaishriram Rathored Sandesh Shende Source Type: research
Use of corticosteroids in non-infectious uveitis - expert consensus in Taiwan
CONCLUSION: While CS are a cornerstone for non-infectious uveitis treatment, their administration requires careful consideration, depending on the clinical situation and the specific type of uveitis. The consensus generated from this article provides a guideline for practitioners in Taiwan, taking into account local health policies and the latest research on the subject. It emphasizes the significance of strategic tapering, the potential for alternative therapies, and the importance of patient-centric care.PMID:38747459 | DOI:10.1080/07853890.2024.2352019 (Source: Annals of Medicine)
Source: Annals of Medicine - May 15, 2024 Category: Internal Medicine Authors: Yo-Chen Chang Tzu-En Kao Ching-Long Chen Yu-Chih Lin De-Kuang Hwang Yih-Shiou Hwang Chun-Ju Lin Wei-Chun Chan Chang-Ping Lin San-Ni Chen Shwu-Jiuan Sheu Source Type: research
Nails in older adults
Ann Med. 2024 Dec;56(1):2336989. doi: 10.1080/07853890.2024.2336989. Epub 2024 May 13.ABSTRACTAs the world's population of adults greater than 60 years old continues to increase, it is important to manage nail disorders that may impact their daily lives. Nail disorders may have significant impact on quality of life due to decreased functionality, extreme pain, or social embarrassment. In this review, we discuss nail disorders affecting older patients, including physiologic, traumatic, drug-induced, infectious, environmental, inflammatory, and neoplastic conditions. Diagnosis of these conditions involves a detailed history,...
Source: Annals of Medicine - May 13, 2024 Category: Internal Medicine Authors: Samantha Jo Albucker Jade Conway Shari R Lipner Source Type: research
The role of gonadal hormones in regulating opioid antinociception
Ann Med. 2024 Dec;56(1):2329259. doi: 10.1080/07853890.2024.2329259. Epub 2024 May 13.ABSTRACTOpioids are the most prescribed drugs for the alleviation of pain. Both clinical and preclinical studies have reported strong evidence for sex-related divergence regarding opioid analgesia. There is an increasing amount of evidence indicating that gonadal hormones regulate the analgesic efficacy of opioids. This review presents an overview of the importance of gonadal steroids in modulating opioid analgesic responsiveness and focuses on elaborating what is currently known regarding the underlyingmechanism. We sought to identify th...
Source: Annals of Medicine - May 13, 2024 Category: Internal Medicine Authors: Qi Xu Lin Jin LuYang Wang YingYing Tang Hui Wu Qing Chen LiHong Sun Source Type: research
Febuxostat provides renoprotection in patients with hyperuricemia or gout: a systematic review and meta-analysis of randomized controlled trials
CONCLUSION: Febuxostat use is associated with a reduced risk of kidney events and a slow decline in eGFR. In addition, the urine albumin to creatinine ratio decreased in febuxostat users. Accordingly, it is an effective drug for delaying the progression of kidney function deterioration in patients with gout.Systematic review registration: PROSPERO CRD42021272591.PMID:38738384 | PMC:PMC11095284 | DOI:10.1080/07853890.2024.2332956 (Source: Annals of Medicine)
Source: Annals of Medicine - May 13, 2024 Category: Internal Medicine Authors: Xiu Hong Yang Bao Long Zhang Yun Cheng Shun Kun Fu Hui Min Jin Source Type: research
Research progress on the relationship between AURKA and tumorigenesis: the neglected nuclear function of AURKA
This article will focus on the role of AURKA in the nucleus and its carcinogenic characteristics that are independent of its kinase activity to provide a theoretical explanation for mechanisms of resistance to kinase inhibitors and a reference for future research on targeted inhibitors.PMID:38738386 | PMC:PMC11095293 | DOI:10.1080/07853890.2023.2282184 (Source: Annals of Medicine)
Source: Annals of Medicine - May 13, 2024 Category: Internal Medicine Authors: Menghua Chen Huijun Zhu Jian Li Danjing Luo Jiaming Zhang Wenqi Liu Jue Wang Source Type: research
The current status of various preclinical therapeutic approaches for tendon repair
This article describes tendon injury and summarizes recent advances in tendon recovery, along with stem cell therapy, gene therapy, Platelet-rich plasma remedy, growth factors, drug treatment, and tissue engineering. Despite the recent fast-growing research in tendon recovery treatment, still, none of them translated to the clinical setting. This review provides a detailed overview of tendon injuries and potential preclinical approaches for treating tendon injuries.PMID:38738394 | PMC:PMC11095292 | DOI:10.1080/07853890.2024.2337871 (Source: Annals of Medicine)
Source: Annals of Medicine - May 13, 2024 Category: Internal Medicine Authors: Wenqing Liang Chao Zhou Yongjun Deng Lifeng Fu Jiayi Zhao Hengguo Long Wenyi Ming Jinxiang Shang Bin Zeng Source Type: research
Academic performance among pharmacy students using virtual vs. face-to-face team-based learning
CONCLUSIONS: Students' performance in virtual TBL vs. FTF TBL in the pharmacy didactic curriculum varies depending on the course content, academic year, and type of assessment.PMID:38738408 | PMC:PMC11095281 | DOI:10.1080/07853890.2024.2349205 (Source: Annals of Medicine)
Source: Annals of Medicine - May 13, 2024 Category: Internal Medicine Authors: Osama A Shoair Source Type: research
Health-related quality of life in patients with generalized pustular psoriasis - a Swedish register study
CONCLUSIONS: Individuals with GPP have a considerable impairment in both generic and dermatology-specific HRQoL. The HRQoL was significantly worse in individuals with GPP compared to individuals with plaque psoriasis. The significant HRQoL impairment of GPP shows the potential value of better healthcare interventions for this multisystem disease.PMID:38738413 | PMC:PMC11095275 | DOI:10.1080/07853890.2024.2341252 (Source: Annals of Medicine)
Source: Annals of Medicine - May 13, 2024 Category: Internal Medicine Authors: Jenny M Norlin Sofia L öfvendahl Marcus Schmitt-Egenolf Source Type: research
Dialysis parameters associated with SARS-CoV-2 infection and prognosis in end-stage kidney disease
CONCLUSION: Acute Covid-19 illness is associated with variations in dialysis parameters of volume status in patients with ESKD. Furthermore, increases in predialysis BP during acute Covid-19 illness are associated with an adverse prognosis in Covid-ESKD patients.PMID:38738416 | PMC:PMC11095274 | DOI:10.1080/07853890.2024.2343890 (Source: Annals of Medicine)
Source: Annals of Medicine - May 13, 2024 Category: Internal Medicine Authors: Rodrigo Bezerra Audes D M Feitosa Odilson M Silvestre Miguel M Fernandes-Silva Roberto B Amazonas Flavio Teles Cibele I S Rodrigues Jose L Lima-Filho Andrei C Sposito Wilson Nadruz Source Type: research
