Clinical outcomes of levalbuterol versus racemic albuterol in pediatric patients with asthma: Propensity score matching approach in a medicaid population
ConclusionThis observational study of children aged 2–18 demonstrated levalbuterol prescription fills were associated with reduced ED visits, but not hospitalizations. Additional research may be necessary to assess this association. Pediatr Pulmonol. © 2016 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - September 30, 2016 Category: Respiratory Medicine Authors: Jing Yuan, Zhiqiang Kevin Lu, Yanjun Zhang, Jun Wu, Bryan L. Love, Richard M. Schulz Tags: Original Article: Outcomes Source Type: research
Efficacy of Inhaled Levalbuterol Compared to Albuterol in Horses with Recurrent Airway Obstruction
Conclusions and clinical importanceLevalbuterol is as effective a bronchodilator as albuterol; although levalbuterol lasts twice as long as albuterol, its duration of action is still too short to make it practical for RAO treatment. (Source: Journal of Veterinary Internal Medicine)
Source: Journal of Veterinary Internal Medicine - April 30, 2016 Category: Veterinary Research Authors: M.G. Arroyo, L.L. Couëtil, N. Nogradi, M.M. Kamarudin, K.M. Ivester Tags: Standard Article Source Type: research
Principal findings of systematic reviews of acute asthma treatment in childhood.
CONCLUSIONS: SRCTs are useful for guiding decisions in acute asthma treatment.
PMID: 26303207 [PubMed - in process] (Source: Journal of Asthma)
Source: Journal of Asthma - February 18, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research
Clinical outcomes and treatment cost comparison of levalbuterol versus albuterol in hospitalized adults with chronic obstructive pulmonary disease or asthma.
CONCLUSION: Clinical outcomes were similar with the use of levalbuterol versus albuterol for exacerbations of COPD or asthma. On average, patients receiving levalbuterol had longer and more costly hospital stays.
PMID: 26025994 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - May 31, 2015 Category: Drugs & Pharmacology Authors: Brunetti L, Poiani G, Dhanaliwala F, Poppiti K, Kang H, Suh DC Tags: Am J Health Syst Pharm Source Type: research
Anti-Inflammatory Effects of Levalbuterol-Induced 11β-Hydroxysteroid Dehydrogenase Type 1 Activity in Airway Epithelial Cells
Matthew J Randall, Shannon F Kostin, Edward J Burgess, Laura R Hoyt, Jennifer L Ather, Lennart K Lundblad and Matthew E Poynter (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - January 12, 2015 Category: Endocrinology Source Type: research
Advances in acute asthma
Purpose of reviewThe purpose of this study is to highlight some of the recent findings related with the management of acute exacerbations in the context of the emergency department setting.
Recent findingsβ2-agonist heliox-driven nebulization significantly increased by 17% [95% confidence interval (CI) 5.2–29.4] peak expiratory flow, and decreased the rate of hospital admissions (risk ratio 0.77, 95% CI 0.62–0.98), compared with oxygen-driven nebulization. Other findings indicate that there is no robust evidence to support the use of intravenous or nebulized magnesium sulphate in adults with severe acute asthma, and t...
Source: Current Opinion in Pulmonary Medicine - November 28, 2014 Category: Respiratory Medicine Tags: ASTHMA: Edited by Nicola A. Hanania and Zuzana Diamant Source Type: research
Economic Impact of Levalbuterol Versus Albuterol in Low-Income Population
The objective of this study is, therefore, to examine the economic impact of levalbuterol versus albuterol on total health care expenditure in a high-risk, low income asthma population. (Source: Value in Health)
Source: Value in Health - November 1, 2014 Category: Global & Universal Authors: J. Yuan, K. Lu Source Type: research
Validation of a population‐based method to assess drug‐induced alterations in the QT interval: a self‐controlled crossover study
ConclusionsQT prolonging effects were common and varied in strength. Our results lend support to past Food and Drug Administration regulatory actions and support the role for ongoing surveillance of drug‐induced QT prolongation. Copyright © 2013 John Wiley & Sons, Ltd. (Source: Pharmacoepidemiology and Drug Safety)
Source: Pharmacoepidemiology and Drug Safety - July 1, 2013 Category: Drugs & Pharmacology Authors: Carlos Iribarren, Alfred D. Round, Jonathan A. Peng, Meng Lu, Jonathan G. Zaroff, Taylor J. Holve, Amit Prasad, Paul Stang Tags: Original Report Source Type: research
A comparison of heart rate changes associated with levalbuterol and racemic albuterol in pediatric cardiology patients.
CONCLUSIONS: Racemic albuterol and levalbuterol were associated with increased heart rate in pediatric cardiology patients. This increase was found to be equivalent.
PMID: 23613097 [PubMed - in process] (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - May 1, 2013 Category: Drugs & Pharmacology Authors: Kelly A, Kennedy A, John BM, Duane B, Lemanowicz J, Little J Tags: Ann Pharmacother Source Type: research
HyperK and Shades of Grey: Myths and Facts about Hyperkalemia Part II
Today we continue our discussion about the myths and facts of hyperkalemia with Dr. Brooks Walsh, author of the Mill Hill Ave Command blog. We also feature contributions from Dr. Stephen Smith, of Dr. Smith's ECG Blog.
If you would like to refresh your memory on Part I visit here.
Dr. Walsh and I spoke about why he thought hyperkalemia presented such a challenge for EMS providers:
"The recognition and treatment of hyperkalemia is one of those areas in medicine wher...
Source: EMS 12-Lead - January 14, 2013 Category: Cardiology Authors: David Baumrind Tags: ems-health-safety ems-topics patient-management Training training-development 12-Lead ECG Brooks Walsh M.D. David Baumrind ems12lead.com hyperkalemia Myths Paramedic Stephen Smith M.D. Source Type: research
